Health Chapters

Brittany Rose · @Brittanylosing

How long to lose 100 lb on a GLP-1

Published

“We’re not in a race — only beat yesterday’s self.”
0:003:38

Chapters

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Brittany’s path was front-loaded: a strong early response, then a long second act toward 100 lb lost. Shortage, a brutal side-effect week, and cash-pay cost all showed up along the way. If you’re bracing for the stretch where progress slows, her second act is the part worth sitting with.

Start
Nov 2022 · ~255+ lb
At filming
~152 lb · ~27 months to −100
Front half
~60 lb in first 6 months
Second act
~40 lb over ~18 months after that
Med path
Mounjaro · peak ~10 mg weekly
Access
Early $25 coupon · later ~$550/fill

Access can unlock the start

Coverage and timing often decide when “ready” feels real

More isn’t always better

A strong mid dose can carry further than a forced jump

Hard weeks happen

Giving it one more week changed her path

Access got her started — cost still shapes the path

When the $25 coupon ended, fills jumped to about $550

We’re not in a race

Only beat yesterday’s self — keep staying the course

Considering

Brittany looked into Mounjaro after seeing someone else’s results, then brought it to her PCP. Cost was the wall until a coupon made a start feel realistic. What “ready” means often includes coverage, assistance programs, and whether the path is sustainable if those change.

Starting

Early months mixed titration, habits, and a short adjunct her clinician used as a bridge. The second month was quieter than the first — which can happen without erasing a strong start. Looking back, she wished she’d stayed longer on a mid dose where loss felt solid and side effects were lighter.

Adjusting & shortage

When her preferred dose wasn’t available, the jump upward hit hard — hard enough that quitting felt close. She gave it another week, and things eased. Her own takeaway was simple: don’t take a higher dose if you don’t need it. Later, when the coupon ended and cash-pay cost landed, habits held but the pace of loss changed again. Access isn’t a one-time event.

The long second act

Most of the pounds came early. The rest took much longer with similar habits. Being okay at an intermediate goal helped her keep going. Near the finish, she and her clinician talked about spacing doses out.

Questions for a clinician

  • If my preferred dose is unavailable, what are safer options than an unwanted jump?
  • What does a maintenance or spacing plan look like near goal weight?
  • How should we think about cost and coverage over a multi-year path?

Also in Setbacks & switches

This story belongs to Brittany Rose. Watch the full video on YouTube